|Title: Long Term Use Of Lamb and Rice Diet?|
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Date Posted：01/26/2009 10:10 PMCopy HTML
Long Term Use Of Lamb and Rice Diet?
Straight Lamb/Rice diets were NEVER meant to be used as a long termed diet. It was designed to be used for a short period of time while the dog was dealing with allergies.
There have been known issues from long term use of this food, Taurine deficiency and heart disease. Chronic liver disease from copper toxicosis. Dogs lose muscle mass - heart is the biggest muscle in the body.
I personally have found that lamb and rice diets doesn't give danes enough fat and protien. The stay way to skinny on this formula.
Email From Dr. Jean Dodd!
There was a time about 10-15 years ago when lamb and rice foods were used for dogs that were allergic or intollerant to standard other foods. But, over the years many dogs have now become reactive to lamb especially, as it now is "overused". When you couple that with the increasing incidence of chronic liver disease from copper toxicosis in young adult dogs of an increasing number of dog breeds, reducing the copper content of commercial foods becomes very important. Most cereal-based kibbles marketed today have 16-33 ppm copper -- way above the 8 ppm minimum or the 11-13 ppm of the foods that are properly balanced in copper. The companies putting in so much copper say that they counteract that by adding more zinc -- what a stupid way to offset the copper (by adding too much of another mineral !). Lamb is a high copper containing food, so we want to restrict its use. See attached. Jean
COPPER TOXICOSIS/ CHRONIC ACTIVE HEPATITIS
W. Jean Dodds, DVM Hemopet
Abnormal accumulation of copper in the liver leads to chronic liver failure, and is an heritable or familial trait recognized in an increasing number of dog breeds, including the West Highland White Terrier, Bedlington Terrier, Skye Terrier, Doberman Pinscher, Labrador Retriever, Keeshond, and American Cocker Spaniel. Other breeds may also be affected. Certain diseases of the liver, especially those that cause blockage of the bile duct or bile flow (cholestasis), also can result in excessive hepatic copper accumulation.
While the level of copper and other metals stored in the body generally tends to be higher in newborns, levels in the dog remain fairly constant throughout life, and are higher than those normally seen in humans. The mean copper concentration in the liver of normal dogs of any breed is 200-400 ppm on a dry weight basis. Dogs with copper toxicosis (also known as chronic active hepatitis) may exhibit concentrations of copper up to 10,000 ppm, while levels of 2000 or greater ppm are excepted to be toxic.
Copper toxicosis, a copper storage disease, is known as Wilson's
disease in people. A similar disease was first recognized in the Bedlington Terrier breed, and there
is now a specific genetic DNA screening test for this trait. Investigators at
Clinical and Pathological Findings
In affected dog breeds, whether the defect is an heritable trait involving the metabolism of copper itself or is a copper storage disorder --- such as might be involved with the Doberman pinscher --- does not affect the outcome. There are three progressive stages of copper toxicosis. In the first stage, the dog is young and not clinically ill, copper levels are beginning to accumulate in the liver, and values are reported to be as high as 1500 ppm. Regardless of the breed, this accumulation begins very early in life, and the rate of accumulation will vary among different breeds and also within individual animals. Wedge biopsy of the liver at this stage will look normal, although special copper stains of biopsy tissue will reveal the excess copper. Stage two of copper toxicosis occurs when the copper level in the liver reaches 2000 ppm. The dog is typically not ill at this point but wedge biopsy of the liver will show hepatitis and is the definitive test to make a diagnosis. Laboratory findings at that time may include an increase in ALT and alkaline phosphatase enzyme levels, but these are nonspecific findings, not necessarily indicative of copper toxicosis. As an elevated ALT enzyme concentration reflects specific hepatocellular disease, it signifies a toxic or other form of injury to the liver cell. There are other pathological changes in blood profiles which can include: low platelet counts, thyroid dysfunction, increase bilirubin in the blood and/or urine, hypoalbuminemia, and anemia. Finally, in stage three disease the dog becomes clinically ill, may have a poor appetite (anorexia), depression, abdominal pain, vomiting, excessive drinking (polydipsia) and urination (polyuria), icterus or jaundice, ascites, high amylase and lipase concentrations, and weight loss, the latter is commonly seen and may be the only clinical sign. These clinical signs usually result from liver necrosis, which is triggered by copper concentrations above 2000 ppm.
In the end stages of copper toxicosis, the concentration of copper in the liver may actually decrease, as the cells that die during the necrotic process are those that have accumulated copper. Because of the progressive nature of the disease, most affected animals are not presented for diagnosis and treatment until the late stages, when clinical symptoms are present, or after some significant body stress event such as a pregnancy. In fact, most of the severely affected, fatal cases in American Cocker Spaniels have occurred in females within a few weeks to months after a pregnancy. An intriguing possibility is the potential relationship between the high incidence of autoimmune hemolytic anemia in American Cocker Spaniels [the breed with highest risk worldwide] and copper toxicosis due to the free radicals produced by copper accumulation. Such a relationship has been suggested in the Bedlington Terrier.
Management and Treatment
Treatment of copper toxicosis can include dietary, medical, or a combination of these methods. Please see the accompanying two-page handout which discuss dietary modification to reduce copper accumulation. When copper accumulation is detected early on and the dog is asymptomatic, initiating treatment at that time may slow down the accumulation of copper before irreversible damage to the liver has occurred. In addition to the dietary changes mentioned in the accompanying handout, chelating agents can be used which bind or chelate copper, thereby enhancing its excretion in the urine or bile. The most commonly used chelating agent is d-penicillamine given at 10-15 mg/kg. However, the use of this copper-chelating drug is somewhat controversial because it also binds zinc, which made deplete tissue levels of zinc and have undesirable side effects. Also, d- penicillamine has other side effects such as anorexia, nausea, and vomiting. In treating some canine cases, the adverse effects of d-penicillamine were counteracted by using a homemade low copper-low protein diet with additional zinc supplementation. Other drugs that have been used in chronic active hepatitis are corticosteroids, such as prednisone, and colchicine. Of the two drugs, prednisone would be preferred as it helps the body excrete excess copper while fighting the inflammation and fibrosis of the liver. Side effects of both these drugs include inducing liver enzyme levels, and colchicine often produces nausea.
Dodds W J. Pet food preservatives and other additives,
Chapter 5. In: Complementary and
Alternative Veterinary Medicine. Mosby,
Dill-Mackey E. Chronic hepatitis in
dogs. Vet Clinics
Dodds W J, Donoghue S.
Interactions of clinical nutrition with genetics, Chapter 8. In: The
Thornburg L P. A study of canine hepatobiliary diseases, Part 4: copper and liver disease. Comp An Pract, 2(7): 3-6, 1988.
Hardy R M. Chronic Hepatitis in dogs: a syndrome. Comp Cont Edu Pract Vet, 8: 904-914, 1986.
Thornburg L P, Polley D, Dimmitt R. The diagnosis and treatment of copper toxicosis in dogs, Can Pract, 11(5): 36-39, 1984.
Lamb and Rice Diets Linda Arndt ~ Canine Nutritional Consultant http://www.greatdanelady.com/articles/lamb_rice_diets.htm _
Here is a portion of an email that Linda sent me.
The Premium Select (lamb & rice) should only be used for skin problems, and not long termed use, even Eagle will tell you that, and that is true of all Lamb/Rice (straight lamb and rice formulas) because it won't hold muscle mass over the long haul. Especially with showing,working and I do not suggest it for pregnancies or young weaning puppies. Use all lamb/rice diets for times of digestive upset and/or food allergies. That is the original intent of all those diets and when we feed them on a daily basis, we have not place to go if there is a real need for them. Linda
Food Allergies: The Truth About Lamb and Rice Mixes http://www.cvm.uiuc.edu/petcolumns/showarticle.cfm?id=113